CPMV Display of SARS-CoV-2 Epitopes

Highly modular plug-and-play bionanotechnology

• Highly adaptable system: should mutants or new strains emerge, the peptides can be updated.

• Precisely controlled and targeted immune response tailored to the epitope of interest.

• Cocktails incorporating multiple immunogenic domains can be produced.

• Possible risk of ADE (antibody-dependent enhancement) or Th2 immunopathology may be avoided through rational design and choice of peptide targets.

MIE-201

MIE-201 is a chimeric plant virus nanoparticle displaying SARS-CoV-2 peptide epitopes manufactured as a microneedle patch.

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• These microneedle vaccine patches can be self-administered. 

• The integrated slow-release provides boosts to the immune system providing an effective immunity shield after a single administration.